翻訳と辞書 Words near each other ・ Historic Automobile Group ・ Historic Barns of Connecticut ・ Historic Blakeley State Park ・ Histon and Impington ・ Histon F.C. ・ Histon railway station ・ Histon Road ・ Histon Road Cemetery, Cambridge ・ Histone ・ Histone 3' UTR stem-loop ・ Histone acetylation and deacetylation ・ Histone acetyltransferase ・ Histone code ・ Histone deacetylase ・ Histone deacetylase 2 ・ Histone deacetylase 5 ・ Histone deacetylase inhibitor ・ Histone demethylase ・ Histone fold ・ Histone gene ・ Histone H1 ・ Histone H2A ・ Histone H2B ・ Histone H2B type 1-C ・ Histone H3 ・ Histone H4 ・ Histone methylation ・ Histone methyltransferase ・ Histone octamer ・ Histone-arginine N-methyltransferase Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Histone deacetylase 5 ： ウィキペディア英語版 Histone deacetylase 5 Histone deacetylase 5 is an enzyme that in humans is encoded by the ''HDAC5'' gene. == Function == Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.〔 AMP-activated protein kinase regulation of the glucose transporter GLUT4 occurs by phosphorylation of HDAC5. HDAC5 is involved in memory consolidation and suggests that development of more selective HDAC inhibitors for the treatment of Alzheimer's disease should avoid targeting HDAC5. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Histone deacetylase 5」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.